When the results of a major long-term, multicenter study, the Trial of Preventing Hypertension (TROPHY), were called into question in two editorials published in the November 2006 issue of the American Journal of Hypertension (AJH), it was inevitable that an exchange of views between the study's supporters and detractors would occur. The essential issue is whether the TROPHY data support the conclusions reported in the New England Journal of Medicine.
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