ABC-transporters Expressed On Endothelial Cell Membranes Efflux Anti-HIV Drugs

New cases in Pous 2064, HIV = 175, AIDS = 26, Death = 2. HIV rate is very high in Housewives than sex workers in Nepal ! ! ! HIV status in Nepal till 2005: Total Adult=70000, Adult Prevalence (15-49)=0.55%, Number of Women (15-49) LWHA=15,310 (22%), HIV Prevalence rate in IDUs=32.7%, HIV prevalence rate in sex worker=3.8%, HIV prevalence rate in client of SW=2.1%. The latest U.N. report shows that 65 million people have been infected with HIV since it was first identified 25 years ago. Twenty five million people have died of AIDS.

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ABC-transporters Expressed On Endothelial Cell Membranes Efflux Anti-HIV Drugs

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ABC-transporters Expressed On Endothelial Cell Membranes Efflux Anti-HIV Drugs - 30-08-2008, 12:40 AM

Researchers have discovered that drug-efflux pumps, belonging to the ATP-binding cassette transporter family, are constitutively expressed on vascular endothelial cells. The study has crucial implications in the persistence of sub-endothelial HIV reservoirs and will be important to the development of future therapies.

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