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Deletion Of Chromatin Remodeling Genes Leads To Leukemia In Mice -
27-08-2008, 09:11 PM
Mice lacking both copies of the Arid4A gene and one copy of the Arid4B gene develop acute myeloid leukemia (AML) and may provide an important animal model for preleukemic and leukemic conditions, according to an article in the Aug. 26 online issue of the Journal of the National Cancer Institute.
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