One might call it a tale of two melanocytes. Given the same genetic mutation, why does one melanocyte shut down growth and become a relatively benign mole, while another rages out of control and develops into deadly melanoma? In trying to tease out the answer to this simple question, researchers have uncovered a protein that stops the growth of melanoma, a cancer that develops from pigment-producing cells in the skin called melanocytes. If this natural anti-cancer agent can be produced and delivered to tumors, it might serve as a targeted chemotherapy for metastatic melanoma, a condition which is "basically untreatable" today.
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