In this study, humoral immunity after vaccination or natural infection was assessed for several common pathogens. Antibodies against varicella zoster virus, measles, and mumps were long-lived (estimated half-lives, >=50 years), and antibodies against tetanus and diphtheria were short-lived (estimated half-lives, 11 and 19 years, respectively). Antibody titers were poorly correlated with peripheral-blood memory B cells.
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