In this trial, patients with mild persistent asthma who were receiving an inhaled corticosteroid twice daily were given the same treatment or were switched either to an inhaler containing a corticosteroid and a long-acting beta-agonist or to a leukotriene modifier. There was no difference in asthma control between the two corticosteroid groups. The patients switched to the leukotriene modifier had more frequent asthma exacerbations, but there was no difference in the percentage of symptom-free days among the three groups.
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