ORIGINAL ARTICLE: Class of Antiretroviral Drugs and the Risk of Myocardial Infarction

New cases in Pous 2064, HIV = 175, AIDS = 26, Death = 2. HIV rate is very high in Housewives than sex workers in Nepal ! ! ! HIV status in Nepal till 2005: Total Adult=70000, Adult Prevalence (15-49)=0.55%, Number of Women (15-49) LWHA=15,310 (22%), HIV Prevalence rate in IDUs=32.7%, HIV prevalence rate in sex worker=3.8%, HIV prevalence rate in client of SW=2.1%. The latest U.N. report shows that 65 million people have been infected with HIV since it was first identified 25 years ago. Twenty five million people have died of AIDS.

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ORIGINAL ARTICLE: Class of Antiretroviral Drugs and the Risk of Myocardial Infarction

NEJM The New England Journal of Medicine

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ORIGINAL ARTICLE: Class of Antiretroviral Drugs and the Risk of Myocardial Infarction - 25-04-2007, 03:40 PM

In patients infected with HIV, the duration of combination antiretroviral therapy has been shown to be associated with the risk of myocardial infarction (MI). In an analysis of data from 23,437 patients, a significant association with risk of MI was found for protease-inhibitor therapy but not for therapy with nonnucleoside reverse-transcriptase inhibitors. This association may be partly explained by the effects of protease inhibitors on serum lipid levels.

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