ORIGINAL ARTICLE: Increased Mortality after Dronedarone Therapy for Severe Heart Fail

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ORIGINAL ARTICLE: Increased Mortality after Dronedarone Therapy for Severe Heart Fail

NEJM The New England Journal of Medicine

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ORIGINAL ARTICLE: Increased Mortality after Dronedarone Therapy for Severe Heart Fail - 18-06-2008, 02:30 PM

Dronedarone is a class III antiarrhythmic drug that has efficacy as a treatment for atrial fibrillation and ventricular arrhythmias. In this clinical trial involving patients with severe heart failure, however, dronedarone was found to increase overall mortality, raising serious concern about the safety of this drug in patients with advanced heart failure.

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