ORIGINAL ARTICLE: Bivalirudin during Primary PCI in Acute Myocardial Infarction

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ORIGINAL ARTICLE: Bivalirudin during Primary PCI in Acute Myocardial Infarction

NEJM The New England Journal of Medicine

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ORIGINAL ARTICLE: Bivalirudin during Primary PCI in Acute Myocardial Infarction - 21-05-2008, 03:02 PM

Bivalirudin is a direct thrombin inhibitor. As compared with a combination of heparin and a glycoprotein IIb/IIIa inhibitor, bivalirudin use resulted in less bleeding and lower 30-day mortality among patients undergoing PCI for acute myocardial infarction. However, bivalirudin was associated with a higher rate of acute stent thrombosis within 24 hours.

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