AUTONOMIC DRUGS
1. According to the transmitter, the efferent nervous system can be devided into
A. Movement and the autonomic nervous system B. Sympathetic and parasympathetic system
C. Cholinergic and norepinephrine nervous system D. Central nervous system and peripheral nerves system
E. sensory and motor nerve
2. about Effect of pilocarpine on eye, which of the following description is correct :
A. Spasm of accommodation B. Reduce intraocular pressure C. Ciliary muscle relaxation
D. Regulatory paralysis E. A + B
3. Neostigmine can be used for myasthenia gravis because :
A. The motor cortex area excitatory effect B. Cholinesterase inhibition and excited NM muscle receptors
C. Ach increase synthetic motor D. Excited muscle muscarinic receptor
E. NN direct excitatory receptor
4. PAM rescue organophosphate poisoning because :
A. Can reactivate cholinesterase B. direct confront Ach C. A muscarinic receptor blocker role
D. N receptor blocker a role E. Confrontation organophosphate molecules of phosphorus toxicity
5. What the following effect irrelevant with atropine muscarinic receptor blocker :
A. visceral smooth muscle relaxation B. Inhibition gland secretion C. lifting small vasospasm
D. accelerated heart rate E. Pupil dilation
6. Atropine rescue organophosphate poisoning, the role is :
A. Easing bronchial spasm B. Reducing bronchial glands and salivary secretion
C. Lower gastrointestinal smooth muscle excitability
D. accelerated heart rate E. Resurrection cholinesterase
8. Effect of pilocarpine is
A. role in the alpha receptor B. Role in the beta receptor C. role in N receptor
D. Muscarinic receptor agonist E. Muscarinic receptor antagonist
11. Atropine used before anesthesia administration was mainly due to
A. Inhibit respiratory gland secretion B. Inhibit urination C. Inhibition defecation
D. Bradycardia prevent E. Inhibition of gastric motility
14. drug that make phosphorylated cholinesterase reactivated is
A. Atropine B. pilocarpine C. Neostigmine D. pralidoxime E. Eserine
16. mechanism of tubocurarine’s muscle relaxant properties is
A. Cholinesterase inhibition B. NM receptor blocker C. NN receptor blocker
D. Inhibit acetylcholine release E. promote the release of acetylcholine
19. NN acetylcholine receptors locate
A. On the skeletal muscle B. Gastrointestinal smooth muscle cells C. Ganglion cells
D. Vascular smooth muscle cells E. myocardial cells.
23 Atropine visceral smooth muscle relaxation is most significant on
A. Bronchial smooth muscle B. Biliary smooth muscle C. Spasticity in gastrointestinal smooth muscle
D. Myometrium E. Pyloric sphincter
25. Norepinephrine synthesis of the basic raw materials for
A. Dopamine B. Dopa C. Histidine D. Tyrosine E. Phenylalanine
26. Effect of pilocarpine mainly for
A. Glaucoma B. Iritis C. Xerostomia oral mucosa D. slow arrhythmia E. A + B
27. Eserine mainly used for
A. Glaucoma B. Myasthenia Gravis C. Anticholinergic drug poisoning
D. postoperative abdominal retension E. Muscle relaxants poisoning
30. NM receptors found primarily in
A. Autonomic nervous Festival B. Adrenomedullin C. Ciliary muscle D. skeletal muscle E. Sphincter
32. disappearance of the Acetylcholine’s effect, mainly dependent on the
A. Cholinesterase hydrolysis B. CYP metabolism C. Choline acetyltransferase role
D. Neural reuptake E. none above is right
33. best choice for postoperative abdominal retension and bladder paralysis is
A. Eserine B. Acetylcholine C. Neostigmine D. galanthamine E. pilocarpine
34. Organophosphate poisoning mechanism
A. Combined with cholinesterase inhibition of cholinesterase B. Activation cholinesterase
C. Adenylate cyclase inhibition D. Make cholinergic neurotransmitter release increased
E. Activation of phosphodiesterase
36. Atropine banned from
A. Gastrointestinal pain B. Cholecystagia C. BPH D. Toxic shock
E. Urinary frequency, urgency and urge magnificent
41. Atropine to cholinergic receptor's role is
A. The same blocking on M, N receptor B. The same blocking on NN, NM receptor
C. Muscarinic receptor blocker, and NM cholinergic receptor blocker
D. muscarinic receptor blocker with a highly selectivity, NN acetylcholine receptor blocker with large doses
E. None above is right
42. Rescue, severe acute organophosphate poisoning what should adopt the following drug treatment
A. Atropine B. Cholinesterase reactivator C. A + B D. Anisodamine E. pilocarpine
44. Succinylcholine of muscle relaxants belongs to
A. Non-depolarizing muscle relaxants B. Depolarizing muscle relaxants C. Competitive muscle relaxants
D. Central muscle relaxants E. NM receptor blockers
50. the rate-limiting enzyme of norepinephrine synthesis from Tyrosine is
A. Butow hydroxylase B. Monoamine oxidase C. Tyrosine hydroxylase
D. hydroxylase E. β Catechol-O-methyl transferase
51. which of the following match is right?
A.alpha receptor-adrenergic - vascular contraction B. Beta receptor-clonidine - bronchial smooth muscle relaxation
C. Muscarinic receptor-nicotine-to dilate D. N--Effect of pilocarpine-muscle contraction
E. Α1 receptor-isoproterenol- lowering blood pressure.
52 Β1 selective receptor agonist is :
A. Adrenaline B. Ephedrine C. Dopamine D. Norepinephrine E. Dobutamine
53. Β2 receptors are mainly located in :
A. Pupillary sphincter on the B. skeletal muscle motor end plates C. Bronchi and vascular smooth muscle
D. Pupil radial muscle E. myocardial cells.
54 major alpha receptor excitatory drug
A. Adrenaline B. Norepinephrine C. Isoproterenol D. ephedrine hydrochloride E. Dobutamine
56. For the extension of the role of local anesthetics and to reduce the absorption time, the measures used to be A. Increase the amount of local anesthetic
B. Increase the concentration of local anesthetic C. Adding a small amount of norepinephrine
D. Adding a small amount of adrenaline E. Adjust pH to drug weak acid
57. Norepinephrine leakage can lead to tissue necrosis, the following types of medicine to combat this role :
A. Atropine B. Prazosin C. Phentolamine D. Cholinergic scopolamine E. Yohimbine
58. Which of the following groups medicine can be used for the treatment of bronchial asthma
A. Norepinephrine, ephedrine B. Dopamine, ephedrine C. Epinephrine, isoproterenol
D. Isoproterenol, dopamine E. Epinephrine, dopamine
63. Epinephrine and norepinephrine similar pharmacological effects are A. accelerated heart rate
B. alpha receptor can be excited C. DBP unchanged or slightly decreased
D. bronchial smooth muscle relaxation E. Treatment of bronchial asthma
66. Dopamine so that the renal vasodilation is
A. Excited beta receptor B. Excited muscarinic receptor C. alpha receptor blocker
D. effect On the dopamine receptors E. Direct effect on the vascular wall
67. Prohibited for subcutaneous and intramuscular injection of the drug is :
A. Adrenaline B. Metaraminol C. Noradrenaline D. Ephedrine E. Phenylephrine
68. For acute bronchial asthma patients should immediately employ:
A. Isoproterenol B. Phenylephrine C. Ephedrine D. Dobutamine E. Atropine
73. Propranolol induced bronchial asthma is mainly due to :
A. Reduce mast cells to release histamine B. Excite muscarinic receptors on the bronchial smooth muscle
C. Direct excite bronchial smooth muscle D. Blocking β2 receptors on the bronchial smooth muscle
E. Blocking β1 receptors on the bronchial smooth muscle
75. pharmacological mechanism of Propranolol treatment of angina is :
A. Coronary artery contraction, the increase in ischemic flow B. Diminished myocardial contractility
C. lower Tension of left ventricular wall, reducing oxygen consumption
D. block beta receptor ,decrease HR E. All of the above
76. Pretreatment with alpha-receptor blockers, and then the original booster dose of adrenaline and blood pressure as follows :
A. Fall B. Increase C. unchanged D. First increase and then drop
E. First drop further increase
77. Phentolamine and vascular expansion of the reasons are :
A. Direct Vasodilation and alpha receptor blocker B. Vasodilation and exciting beta receptor
C. alpha receptor blocker D. Excite beta receptor E. Direct dilate vessel
81. Adrenaline has overturned the role of the drug is
A. Muscarinic receptor antagonist B. N receptor antagonist C.alpha receptor antagonist
D. Beta receptor antagonist E. None above is right
83. both alpha and beta receptor blocking drug is
A. Phentolamine B. Prazosin C. Propranolol D. Atenolol E. TCH
85. mechanism of Propranolol in the antithyroid is
A. Inhibition of iodide uptake B. T4 thyroxine suppression of synthesis
C. Inhibit 5-deiodinase, reducing three triiodothyronine T3 generation D. TSH antagonistic role
E. none above is right
Linear Mode
