| Cholesterol feeds Prostate cancer -
31-10-2005, 11:09 PM
FACTS ON PROSTATE CANCER
Cholesterol feeds Prostate cancer
High cholesterol levels accelerate the growth of prostate tumours, research has found.
A team from Boston's Children Hospital also found that cholesterol-lowering statin drugs may inhibit prostate cancer growth.
The findings may help explain why prostate cancer is more common in the West, where diets tend to be high in cholesterol.
Details are published in the Journal of Clinical Investigation.
Rates of prostate cancer in rural parts of China and Japan, where low fat diets are the norm, are up to 90% less than in the West.
Yet when Eastern men migrate to the West their chances of being diagnosed with prostate cancer increase.
This has led doctors to suspect that environmental factors - such as diet - may play a significant role in the development of the disease.
Radical prostatectomy for prostate Ca
This 10 year study comparing survival in patients with eraly prostate carcinoma receiving either radical or watchful waiting demonstrates reduced disease specific and overall mortality on the surgically treated group.
NEJM 2005;352: 1877-1984
This study examined mortality in 695 men randomised to receive either radical prostatectomy or watchful waiting for early prostate cancer. During a median of 8.2 years of follow-up, 83 men in the surgery group and 106 men in the watchful-waiting group died (P=0.04). In 30 of the 347 men assigned to surgery (8.6 percent) and 50 of the 348 men assigned to watchful waiting (14.4 percent), death was due to prostate cancer. The study reveals a decreased disease specific and overall mortality following radical prostatectomy in men treated with radical prostatectomy vs conservative management.
Author: Steve Davies
Last edited by sashank; 31-10-2005 at 11:21 PM.
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