Thanks friends.
Well, I want to talk something about
Ectrodactyly
Ectrodactyly, commonly known as lobster claw syndrome, sometimes known as Karsch-Neugebauer syndrome, is a rare congenital deformity of the hand where the middle digit is missing, and the hand is cleft where the metacarpal of the finger should be. This split gives the hands the appearance of lobster claws. Ectrodactyly may also be known as "lobster claw hand", "split hand deformity", "split hand/foot malformation (SHFM)", "cleft hand", "ectrodactilia of the hand" or "Karsch-Neugebauer syndrome".
Ectrodactyly is an inherited condition, and often occurs in both the hands and the feet. Its inheritance pattern is autosomal dominant. It affects about 1 in 90,000 babies, with males and females equally likely to be affected. It is treated surgically to improve function and appearance. Prosthetics may also be used, and genetic counselling given to parents with the condition.
There are different forms of the disorder and each of them are connected with a different genetic mutation. Type I, the most frequent form has been found to be a mutation on chromosome 7 in a region that contains two homeobox genes, DLX5 and DLX6.
A 30 year ectrodactylic female gave ectrodactylic baby.
This baby girl won a motor bike in a lottery ticket only few days after her birth despite of her social stigma. Interesting !!!
Since this disease runs in family I have made a pedigree chart of this female. Please see the attachment.