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Join Date: Apr 2007 Location: kathmandu | | | HPV Vaccine Offers No Treatment Benefit -
20-08-2007, 04:04 AM
HPV Vaccine Offers No Treatment Benefit
Vaccination against human papillomavirus types 16 and 18 has no therapeutic effect in women already infected with HPV, reports a study in JAMA.
Researchers examined the efficacy of the bivalent HPV-16/18 vaccine among nearly 2200 young women who were positive for HPV DNA and were randomized to receive three doses of either the vaccine or a control hepatitis A vaccine over 6 months.
Clearance of HPV types 16 and 18, among others, did not differ between the groups at 6 or 12 months after enrollment. This held true in analyses stratified according to various factors, including HPV viral load, time since sexual initiation, and oral contraceptive use.
Noting that the results are consistent with those for the FDA-approved quadrivalent HPV vaccine, an editorialist says the findings reinforce that "HPV vaccine does not have a role in treatment" of women with abnormal Pap results or positive HPV DNA tests.
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