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Join Date: Apr 2007 Location: kathmandu | | | Hepatitis B protection -
13-08-2007, 04:03 AM
Older Teens May Lose Protection Against Hepatitis B A study raises the possibility that children who received hepatitis B vaccine as infants may be losing immunity as they reach adolescence.
The study, in Pediatrics, involved administering booster doses to 212 adolescents age 10 to 14 and 166 children age 5 to 7. All were born to hepatitis B surface antigen-negative mothers and received the first dose of vaccine within a week of their births.
The study found that 97% of 5-year-olds had an anamnestic response to the booster dose, compared with 60% of 14-year-olds.
The authors said the diminished response among the older adolescents "might indicate waning immunity." They theorized that a booster dose by early adolescence could offer longer-term protection, although that needs to be tested.
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