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also could anyone please explain cellular repiration to me
I am absolutely lost in biochemistry....there are so many reactions for glycolysis,the kreb's cycle and oxidative phosphorylation that I have no clue whats going on....
Take it easy greg. Sofar as reactions are concerned you must learn them by heart and by time it will be no problem at all to remember all of them. However you must be clear of the fact why they are there.
It is (not only but mainly) about producing maximum possible ATP.
Just draw a sketch: what are inputs and what comes out, and where the outputs are used.
Simplified: anaerob.
Glc ---->lactat // 2 ATP
Aerob. 1. Glc ---->Pyruvate // 2 ATP
2. Pyruvate---->Acetyl-CoA // NADH/H+(=3ATP)
3. Acetyl-CoA in Krebs cycle----> 3NADH/H+(=3*3ATP), FADH2(=2ATP), GTP
4. Oxd Phosp.---> NADH/H+, FADH2 are used as proton donator, they create proton gradient in mitoch. intermembrane, which is needed to generate ATP out of ADP + P.
So in aerobic condition, a cell can generate 16 times more ATPs than in anaerobic condition. This is all you need to understand. Erythrocytes eg can only produce 2 ATP per glycolysis per Glc since mitoch. are missing for ox. phosph.
Moreover krebs cycle is a junction for many other metabol. processes. Like Gluconeogenesis.
thanks rajiv, you've really simplified it and I understand the basic concepts.
I visited the library and found a great biochem book called lippincott's biochemistry, it seems pretty straight forward and easy to understand.
in biochemistry....there are so many reactions for glycolysis,the kreb's cycle and oxidative phosphorylation that I have no clue whats going on....
Re: biochemistry -
15-03-2007, 07:21 AM
Re: biochemistry -
16-03-2007, 03:08 AM
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