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  1. EARLY RELEASE: Noninvasive Monitoring of Tumors
  2. EARLY RELEASE: Detection of Mutations in EGFR in Circulating Lung-Cancer Cells
  3. PERSPECTIVE: Why Doctors Should Worry about Preemption
  4. PERSPECTIVE: Collective Accountability for Medical Care -- Toward Bundled Medicare Pa
  5. ORIGINAL ARTICLE: Intensity of Renal Support in Critically Ill Patients with Acute Ki
  6. ORIGINAL ARTICLE: Vasopressin and Epinephrine vs. Epinephrine Alone in Cardiopulmonar
  7. ORIGINAL ARTICLE: Motesanib Diphosphate in Progressive Differentiated Thyroid Cancer
  8. ORIGINAL ARTICLE: A Population Study of Endomyocardial Fibrosis in a Rural Area of Mo
  9. SPECIAL ARTICLE: Electronic Health Records in Ambulatory Care -- A National Survey of
  10. REVIEW ARTICLE: Mechanisms of Disease: Effect of In Utero and Early-Life Conditions o
  11. IMAGES IN CLINICAL MEDICINE: Renal Osteodystrophy of the Palate
  12. IMAGES IN CLINICAL MEDICINE: Bilateral Kidney Calcifications
  13. CLINICAL PROBLEM-SOLVING: A Gut Feeling
  14. EDITORIAL: Dialysis in Acute Kidney Injury -- More Is Not Better
  15. CLINICAL IMPLICATIONS OF BASIC RESEARCH: Removing the Golden Coat of Staphylococcus a
  16. CORRESPONDENCE: Medical-Device Safety and the FDA
  17. CORRESPONDENCE: Mechanical Ventilation and Disuse Atrophy of the Diaphragm
  18. CORRESPONDENCE: Cholesterol Gene Polymorphisms and Cardiovascular Events
  19. CORRESPONDENCE: Imiquimod for Vulvar Intraepithelial Neoplasia
  20. CORRESPONDENCE: Correction: Drug-Review Deadlines and Safety Problems
  21. CORRESPONDENCE: Hydroxyurea for Sickle Cell Anemia
  22. CORRESPONDENCE: More on Melanoma with Transdifferentiation
  23. CORRESPONDENCE: Peculiar Morphology of Stones in Primary Hyperoxaluria
  24. BOOK REVIEW: Electrical Diseases of the Heart: Genetics, Mechanisms, Treatment, Preve
  25. BOOK REVIEW: Diastolic Heart Failure
  26. BOOK REVIEW: Osteoporosis
  27. BOOK REVIEW: Platelets in Hematologic and Cardiovascular Disorders: A Clinical Handbo
  28. CORRECTIONS: Weekly Paclitaxel in the Adjuvant Treatment of Breast Cancer
  29. CORRECTIONS: Metformin versus Insulin for the Treatment of Gestational Diabetes
  30. CME: Intensity of Renal Support in Critically Ill Patients with Acute Kidney Injury
  31. CME: Vasopressin and Epinephrine vs. Epinephrine Alone in Cardiopulmonary Resuscitati
  32. CME: A Gut Feeling
  33. PERSPECTIVE: Health Care Reform in Massachusetts -- Expanding Coverage, Escalating Co
  34. PERSPECTIVE: Focus on Research: From Darwin's Finches to Canaries in the Coal Mine --
  35. ORIGINAL ARTICLE: Rivaroxaban versus Enoxaparin for Thromboprophylaxis after Hip Arth
  36. ORIGINAL ARTICLE: Rivaroxaban versus Enoxaparin for Thromboprophylaxis after Total Kn
  37. ORIGINAL ARTICLE: Angiotensin II Blockade and Aortic-Root Dilation in Marfan's Syndro
  38. SPECIAL ARTICLE: Polygenes, Risk Prediction, and Targeted Prevention of Breast Cancer
  39. CLINICAL PRACTICE: Acute Calculous Cholecystitis
  40. VIDEOS IN CLINICAL MEDICINE: Placement of a Femoral Venous Catheter
  41. IMAGES IN CLINICAL MEDICINE: Systemic Sclerosis and Acral Osteolysis
  42. IMAGES IN CLINICAL MEDICINE: Spontaneous Thrombolysis of an Obstructed Mechanical Aor
  43. CASE RECORDS OF THE MASSACHUSETTS GENERAL HOSPITAL: Case 20-2008 -- A 57-Year-Old Wom
  44. EDITORIAL: New Anticoagulants -- The Path from Discovery to Clinical Practice
  45. EDITORIAL: A Small Molecule for a Large Disease
  46. SOUNDING BOARD: Informing Candidates for Solid-Organ Transplantation about Donor Risk
  47. CORRESPONDENCE: Hypereosinophilic Syndrome and Mepolizumab
  48. CORRESPONDENCE: Red-Cell Storage and Complications of Cardiac Surgery
  49. CORRESPONDENCE: Case-Control Study of Smoking and Death in India
  50. CORRESPONDENCE: Acinetobacter Infection
  51. CORRESPONDENCE: Does Preventive Care Save Money?
  52. CORRESPONDENCE: Case 4-2008: A Pregnant Woman with a Swollen Left Breast and Dyspnea
  53. CORRESPONDENCE: Early Coenzyme Q10 Supplementation in Primary Coenzyme Q10 Deficiency
  54. BOOK REVIEW: Low Income, Social Growth, and Good Health: A History of Twelve Countrie
  55. BOOK REVIEW: Side Effects: A Prosecutor, a Whistleblower, and a Bestselling Antidepre
  56. BOOK REVIEW: Medical Malpractice
  57. BOOK REVIEW: Truth, Lies, and Public Health: How We Are Affected When Science and Pol
  58. CME: Rivaroxaban versus Enoxaparin for Thromboprophylaxis after Hip Arthroplasty
  59. CME: Acute Calculous Cholecystitis
  60. CME: Case 20-2008: A 57-Year-Old Woman with Abdominal Pain and Weakness after Gastric
  61. EARLY RELEASE: Electronic Health Records in Ambulatory Care -- A National Survey of P
  62. PERSPECTIVE: Keeping Pace with the Times -- The Genetic Information Nondiscrimination
  63. PERSPECTIVE: Focus on Research: Cancer Immunotherapy -- The Endgame Begins
  64. ORIGINAL ARTICLE: Rhythm Control versus Rate Control for Atrial Fibrillation and Hear
  65. ORIGINAL ARTICLE: Increased Mortality after Dronedarone Therapy for Severe Heart Fail
  66. ORIGINAL ARTICLE: Electrocardiographic Abnormalities and Sudden Death in Myotonic Dys
  67. ORIGINAL ARTICLE: Brief Report: Treatment of Metastatic Melanoma with Autologous CD4+
  68. REVIEW ARTICLE: Molecular Origins of Cancer: Cancer Immunology
  69. IMAGES IN CLINICAL MEDICINE: Central Hemiretinal Arterial Occlusion
  70. IMAGES IN CLINICAL MEDICINE: Bladder Foreign Body
  71. CASE RECORDS OF THE MASSACHUSETTS GENERAL HOSPITAL: Case 19-2008 -- A 63-Year-Old HIV
  72. EDITORIAL: Rhythm Control in Atrial Fibrillation -- One Setback after Another
  73. SOUNDING BOARD: Over-the-Counter Sales of Statins and Other Drugs for Asymptomatic Co
  74. CLINICAL IMPLICATIONS OF BASIC RESEARCH: Tumor Necrosis Factor {alpha** and Colitis-As
  75. CORRESPONDENCE: Cetuximab-Induced Anaphylaxis and IgE Specific for Galactose-{alpha**-
  76. CORRESPONDENCE: Vasopressin in Septic Shock
  77. CORRESPONDENCE: Five Genetic Variants Associated with Prostate Cancer
  78. CORRESPONDENCE: Genetics of Warfarin Response
  79. CORRESPONDENCE: Acute Pulmonary Embolism
  80. CORRESPONDENCE: Imatinib as a Possible Cause of Severe Rhabdomyolysis
  81. BOOK REVIEW: Handbook of PTSD: Science and Practice; Haunted by Combat: Understanding
  82. CME: Rhythm Control versus Rate Control for Atrial Fibrillation and Heart Failure
  83. CME: Case 19-2008: A 63-Year-Old HIV-Positive Man with Cutaneous Merkel-Cell Carcinom
  84. CME: Over-the-Counter Sales of Statins and Other Drugs for Asymptomatic Conditions
  85. CME: Intensive Blood Glucose Control and Vascular Outcomes in Patients with Type 2 Di
  86. CME: Graves' Disease
  87. CME: Age-Related Macular Degeneration
  88. PERSPECTIVE: Redefining Quality -- Implications of Recent Clinical Trials
  89. PERSPECTIVE: Focus on Research: Vaccine Preparedness -- Are We Ready for the Next Inf
  90. ORIGINAL ARTICLE: Effects of Intensive Glucose Lowering in Type 2 Diabetes
  91. ORIGINAL ARTICLE: Intensive Blood Glucose Control and Vascular Outcomes in Patients w
  92. ORIGINAL ARTICLE: A Clinical Trial of a Whole-Virus H5N1 Vaccine Derived from Cell Cu
  93. ORIGINAL ARTICLE: Chromosome 6p22 Locus Associated with Clinically Aggressive Neurobl
  94. CLINICAL PRACTICE: Graves' Disease
  95. REVIEW ARTICLE: Medical Progress: Age-Related Macular Degeneration
  96. IMAGES IN CLINICAL MEDICINE: Rupture of a Calcified Achilles' Tendon
  97. IMAGES IN CLINICAL MEDICINE: Severe Kyphosis
  98. CASE RECORDS OF THE MASSACHUSETTS GENERAL HOSPITAL: Case 18-2008 -- A 68-Year-Old Man
  99. EDITORIAL: Intensive Glycemic Control in the ACCORD and ADVANCE Trials
  100. EDITORIAL: Glycemic Targets and Cardiovascular Disease
  101. EDITORIAL: Neuroblastoma -- Linking a Common Allele to a Rare Disease
  102. CORRESPONDENCE: A New Arenavirus in Transplantation
  103. CORRESPONDENCE: Thrombus Aspiration during Primary Percutaneous Coronary Intervention
  104. CORRESPONDENCE: Drug-Eluting Stents vs. Coronary-Artery Bypass Grafting
  105. CORRESPONDENCE: Endovascular vs. Open Repair of Abdominal Aortic Aneurysms
  106. CORRESPONDENCE: Rituximab in Relapsing-Remitting Multiple Sclerosis
  107. CORRESPONDENCE: Lumbar Spinal Stenosis
  108. CORRESPONDENCE: More on Ovarian Insufficiency with Imatinib
  109. CORRESPONDENCE: Propranolol for Severe Hemangiomas of Infancy
  110. BOOK REVIEW: Max Perutz and the Secret of Life
  111. BOOK REVIEW: The Comatose Patient
  112. BOOK REVIEW: Nidoviruses
  113. EARLY RELEASE: Breast-Feeding, Antiretroviral Prophylaxis, and HIV
  114. EARLY RELEASE: Effects of Early, Abrupt Weaning for HIV-free Survival of Children in
  115. EARLY RELEASE: Extended Antiretroviral Prophylaxis to Reduce Breast-Milk HIV-1 Transm
  116. PERSPECTIVE: A New Attack on Malaria
  117. PERSPECTIVE: Coagulation and Adulteration -- Building on Science and Policy Lessons f
  118. ORIGINAL ARTICLE: Aliskiren Combined with Losartan in Type 2 Diabetes and Nephropathy
  119. ORIGINAL ARTICLE: Hypothermia Therapy after Traumatic Brain Injury in Children
  120. ORIGINAL ARTICLE: Contaminated Heparin Associated with Adverse Clinical Events and Ac
  121. SPECIAL ARTICLE: Socioeconomic Inequalities in Health in 22 European Countries
  122. REVIEW ARTICLE: Drug Therapy: Chemotherapy-Induced Nausea and Vomiting
  123. IMAGES IN CLINICAL MEDICINE: Ethmoid Mucocele Causing Visual Impairment
  124. IMAGES IN CLINICAL MEDICINE: Bilateral Peritonsillar Abscesses
  125. CLINICAL PROBLEM-SOLVING: A Joint Venture
  126. EDITORIAL: Aliskiren and Dual Therapy in Type 2 Diabetes Mellitus
  127. EDITORIAL: Heparin Comes Clean
  128. EDITORIAL: Beyond Health Care -- Socioeconomic Status and Health
  129. CLINICAL IMPLICATIONS OF BASIC RESEARCH: Metabolism and Therapeutic Angiogenesis
  130. CORRESPONDENCE: DNA Methylation in Lung Cancer
  131. CORRESPONDENCE: Abacavir Hypersensitivity
  132. CORRESPONDENCE: Bare-Metal versus Drug-Eluting Coronary Stents
  133. CORRESPONDENCE: Reduced Exposure to Calcineurin Inhibitors in Renal Transplantation
  134. CORRESPONDENCE: Nasal CPAP for Very Preterm Infants
  135. CORRESPONDENCE: Chronic Hepatitis E and Organ Transplants
  136. CORRESPONDENCE: Phototherapy for Neonatal Jaundice
  137. BOOK REVIEW: Do No Harm: How a Magic Bullet for Prostate Cancer Became a Medical Quan
  138. BOOK REVIEW: Urological Oncology
  139. BOOK REVIEW: Medical Care of the Pregnant Patient
  140. BOOK REVIEW: Heart Disease in Pregnancy
  141. CORRECTIONS: Treatment of Patients with the Hypereosinophilic Syndrome with Mepolizum
  142. CME: Aliskiren Combined with Losartan in Type 2 Diabetes and Nephropathy
  143. CME: Chemotherapy-Induced Nausea and Vomiting
  144. CME: A Joint Venture
  145. PERSPECTIVE: The Moral of the Story
  146. PERSPECTIVE: Exploiting a Research Underclass in Phase 1 Clinical Trials
  147. ORIGINAL ARTICLE: A Comparison of Aprotinin and Lysine Analogues in High-Risk Cardiac
  148. ORIGINAL ARTICLE: Methylnaltrexone for Opioid-Induced Constipation in Advanced Illnes
  149. ORIGINAL ARTICLE: A Placebo-Controlled Trial of Prucalopride for Severe Chronic Const
  150. ORIGINAL ARTICLE: Multiple Genetic Loci for Bone Mineral Density and Fractures
  151. CLINICAL PRACTICE: Precocious Puberty
  152. REVIEW ARTICLE: Current Concepts: Hepatopulmonary Syndrome -- A Liver-Induced Lung Va
  153. VIDEOS IN CLINICAL MEDICINE: Cricothyroidotomy
  154. IMAGES IN CLINICAL MEDICINE: The Aorta in Osteoporosis
  155. IMAGES IN CLINICAL MEDICINE: Severe Constipation
  156. CASE RECORDS OF THE MASSACHUSETTS GENERAL HOSPITAL: Case 17-2008 -- A 63-Year-Old Man
  157. EDITORIAL: The Aprotinin Story -- Is BART the Final Chapter?
  158. EDITORIAL: Opioid Side Effects -- Mechanism-Based Therapy
  159. EDITORIAL: The Long and Short of a Constipation-Reducing Medication
  160. EDITORIAL: Bona Fide Genetic Associations with Bone Mineral Density
  161. CORRESPONDENCE: Local Paclitaxel Delivery in Peripheral Vascular Disease
  162. CORRESPONDENCE: Cardiovascular Events during World Cup Soccer
  163. CORRESPONDENCE: Hutchinson-Gilford Progeria Syndrome
  164. CORRESPONDENCE: Effect of Cost Sharing on Screening Mammography
  165. CORRESPONDENCE: Systemic Lupus Erythematosus
  166. CORRESPONDENCE: Acute Lower Respiratory Tract Infection
  167. CORRESPONDENCE: Cortical Arousal in Children with Severe Enuresis
  168. BOOK REVIEW: Tumor Angiogenesis: Basic Mechanisms and Cancer Therapy
  169. BOOK REVIEW: Blood Matters: From Inherited Illness to Designer Babies, How the World
  170. BOOK REVIEW: Obesity: Genomics and Postgenomics
  171. CORRECTIONS: Gestational Diabetes -- Setting Limits, Exploring Treatments
  172. CME: Precocious Puberty
  173. CME: Hepatopulmonary Syndrome -- A Liver-Induced Lung Vascular Disorder
  174. CME: Case 17-2008: A 63-Year-Old Man with Metastatic Renal-Cell Carcinoma
  175. EARLY RELEASE: Dialysis in Acute Kidney Injury -- More Is Not Better
  176. EARLY RELEASE: Intensity of Renal Support in Critically Ill Patients with Acute Kidne
  177. PERSPECTIVE: DTCA for PTCA -- Crossing the Line in Consumer Health Education?
  178. PERSPECTIVE: Human Rights: Driven to a Fiery Death -- The Tragedy of Self-Immolation
  179. ORIGINAL ARTICLE: Facilitated PCI in Patients with ST-Elevation Myocardial Infarction
  180. ORIGINAL ARTICLE: Bivalirudin during Primary PCI in Acute Myocardial Infarction
  181. ORIGINAL ARTICLE: Brief Report: Effect of Gene Therapy on Visual Function in Leber's
  182. ORIGINAL ARTICLE: Brief Report: Safety and Efficacy of Gene Transfer for Leber's Cong
  183. SPECIAL ARTICLE: The Collective Dynamics of Smoking in a Large Social Network
  184. CLINICAL THERAPEUTICS: Sublingual Immunotherapy
  185. IMAGES IN CLINICAL MEDICINE: Ocular Trauma Due to a Water-Bottle Cap
  186. IMAGES IN CLINICAL MEDICINE: Starr-Edwards Heart Valves
  187. CASE RECORDS OF THE MASSACHUSETTS GENERAL HOSPITAL: Case 16-2008 -- A 46-Year-Old Wom
  188. EDITORIAL: Peer Review in the Balance
  189. EDITORIAL: Does Thrombolytic Therapy Facilitate or Foil Primary PCI?
  190. EDITORIAL: Antithrombotic Therapy to Support Primary PCI
  191. EDITORIAL: Preliminary Results of Gene Therapy for Retinal Degeneration
  192. EDITORIAL: Stranded in the Periphery -- The Increasing Marginalization of Smokers
  193. CLINICAL IMPLICATIONS OF BASIC RESEARCH: How HIV Guts the Immune System
  194. CORRESPONDENCE: Severe Anemia in Malawian Children
  195. CORRESPONDENCE: Multifactorial Intervention and Mortality in Type 2 Diabetes
  196. CORRESPONDENCE: Iron-Overload-Related Disease in HFE Hereditary Hemochromatosis
  197. CORRESPONDENCE: Catheter Ablation in Patients with ICDs
  198. CORRESPONDENCE: Athletes with Repolarization Abnormalities
  199. CORRESPONDENCE: Neurogenic Orthostatic Hypotension
  200. CORRESPONDENCE: A PCSK9 Missense Variant Associated with a Reduced Risk of Early-Onse
  201. BOOK REVIEW: Comprehensive Pediatric Hospital Medicine
  202. BOOK REVIEW: Popular Medicines: An Illustrated History
  203. BOOK REVIEW: Psychoanalysis and Narrative Medicine
  204. BOOK REVIEW: Musicophilia: Tales of Music and the Brain
  205. CME: Facilitated PCI in Patients with ST-Elevation Myocardial Infarction
  206. CME: Sublingual Immunotherapy
  207. CME: Case 16-2008: A 46-Year-Old Woman with Bone Pain
  208. EARLY RELEASE: Chromosome 6p22 Locus Associated with Clinically Aggressive Neuroblast
  209. EARLY RELEASE: The Aprotinin Story -- Is BART the Final Chapter?
  210. EARLY RELEASE: DTCA for PTCA -- Crossing the Line in Consumer Health Education?
  211. EARLY RELEASE: A Comparison of Aprotinin and Lysine Analogues in High-Risk Cardiac Su
  212. PERSPECTIVE: Vaccines and Autism Revisited -- The Hannah Poling Case
  213. PERSPECTIVE: Like Night and Day -- Shedding Light on Off-Hours Care
  214. ORIGINAL ARTICLE: Class-Sparing Regimens for Initial Treatment of HIV-1 Infection
  215. ORIGINAL ARTICLE: Use of Multiple Biomarkers to Improve the Prediction of Death from
  216. ORIGINAL ARTICLE: Cardiac Troponin and Outcome in Acute Heart Failure
  217. ORIGINAL ARTICLE: Efficacy and Safety of Recombinant Activated Factor VII for Acute I
  218. CLINICAL PRACTICE: Rotator-Cuff Failure
  219. REVIEW ARTICLE: Medical Progress: Biomarkers in Heart Failure
  220. IMAGES IN CLINICAL MEDICINE: Keratoderma Blennorrhagica
  221. IMAGES IN CLINICAL MEDICINE: Giant Ovarian Cyst
  222. CASE RECORDS OF THE MASSACHUSETTS GENERAL HOSPITAL: Case 15-2008 -- A 55-Year-Old Man
  223. EDITORIAL: Initial Treatment for HIV Infection -- An Embarrassment of Riches
  224. EDITORIAL: Multiple Biomarker Panels for Cardiovascular Risk Assessment
  225. EDITORIAL: Intracerebral Hemorrhage -- Improving Outcome by Reducing Volume?
  226. CLINICAL DECISIONS: Management of Carotid Stenosis -- Polling Results
  227. CORRESPONDENCE: Mild Traumatic Brain Injury in U.S. Soldiers Returning from Iraq
  228. CORRESPONDENCE: Outcomes 18 Months after the First Human Partial Face Transplantation
  229. CORRESPONDENCE: Selective Publication of Antidepressant Trials
  230. CORRESPONDENCE: Physicians and Execution
  231. CORRESPONDENCE: Perspective Roundtable: Lethal Injection
  232. CORRESPONDENCE: Letting the Genome Out of the Bottle
  233. CORRESPONDENCE: Serotonin Syndrome Associated with Triptan Monotherapy
  234. BOOK REVIEW: The Longevity Revolution: The Benefits and Challenges of Living a Long L
  235. BOOK REVIEW: Fundamentals of the Stem Cell Debate: The Scientific, Religious, Ethical
  236. BOOK REVIEW: Sex Differences in the Brain: From Genes to Behavior
  237. CME: Class-Sparing Regimens for Initial Treatment of HIV-1 Infection
  238. CME: Cardiac Troponin and Outcome in Acute Heart Failure
  239. CME: Case 15-2008: A 55-Year-Old Man with an Elevated Prostate-Specific Antigen Level
  240. CME: Hyperglycemia and Adverse Pregnancy Outcomes
  241. CME: Metformin versus Insulin for the Treatment of Gestational Diabetes
  242. CME: Case 14-2008: A 78-Year-Old Man with Anergia and Anhedonia Associated with Cardi
  243. EARLY RELEASE: Neuroblastoma -- Linking a Common Allele to a Rare Disease
  244. EARLY RELEASE: Chromosome 6p22 Locus Associated with Clinically Aggressive Neuroblast
  245. PERSPECTIVE: Planning for the Future -- Long-Term Care and the 2008 Election
  246. PERSPECTIVE: Etiquette-Based Medicine
  247. ORIGINAL ARTICLE: Hyperglycemia and Adverse Pregnancy Outcomes
  248. ORIGINAL ARTICLE: Metformin versus Insulin for the Treatment of Gestational Diabetes
  249. ORIGINAL ARTICLE: Sudden Cardiac Arrest Associated with Early Repolarization
  250. ORIGINAL ARTICLE: Brief Report: Left Cardiac Sympathetic Denervation for Catecholamin