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Re: Staging of diastolic dysfunction - 22-07-2007, 05:09 PM

angel66 has already given and beside this according to American Heart Association diastolic function can also be quantitated by echocardiography:

1. Mild diastolic dysfunction or “impaired relaxation” (Grade 1)
  • Could also be subdivided with likely normal resting LV filling pressures (mild) and likely elevated left ventricular enddiastolic pressure (LVEDP) — mild to moderate; and
  • Usually no symptoms at rest with mild exercise limitation.
2. Moderate diastolic dysfunction or “pseudonormal” (Grade 2)
  • Associated with elevated LVEDP; and
  • Associated with exertional dyspnea and moderate functional impairment.
3. Severe diastolic dysfunction or “restrictive physiology” (Grade 3)
  • Associated with high LV filling pressures (LVEDP);
  • Dyspnea with minimal exertion and marked functional impairment; and
  • May be further classified as Grade 4, if the mitral Doppler inflow is not reversed with Valsalva’s maneuver.
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