[rbineeta]

After reading the link mentioned in Dr Tuladhar's thread I can not but feel there is something authors of this paper have chosen not to disclose as to why trial was prematurely terminated for 'safety' reason. If Gati was too good then why do you say it was terminated for safety reason. Or does it imply that Cefixime is unsafe and it license should be withdrawn for use in Typhoid.
May be I am not as clever as these authors are that I can not get my head round this.

The unfortunate gentleman who died in cefixime group entered in trial after 10 days of illness !!! One can argue that the outcome would not have been different even if he was in the Gati group.

I want to ask Oxford Reasearch Council -- How did they find it ethical to approve study of a drug which is not licensed in the UK was withdrawn from the European market.

Finally, Dr Pandit just because you were the first author and hence prepared to take Gati if you get ( God forbid) typhoid in Maryland does not mean that poor defenseless Nepalese should be exposed to its risks. Sometimes KAG REALLY TAKES KAN AWAY