Japenese encephalitis JE vaccine
JE is a mosquito borne arboviral infection predominant cause of viral encephalitis in Asia .
Children below 15 years are predominantly affected ;most of JE infection develope subclinical rather than overt symptoms.
serious outcomes in the surviors include- paralysis , coma , neuroparalysis .
Prevalence
Disease mainly occur in the rural areas.
VACCINATION IS SINGLEMOST IMPORTANT CONTROL MEASURE
JE-vaccine -GCC inj. has proven ot protective against JE.
It is purified preparation of the inactivated JE virus derived from the mice which is artificially inoculated with Nakayama strain.
IMMUNISATION SCHEME
Primary immunisation consist of :
3 doses of 1 ml for persons > 3 years of age at an interval of 0/1-2 wks/1year
3 doses of 0.5 ml for persons < 3 years of age at an interval of 0/1-2 wks/1year
Booster
At the age of 6 years and 12 years
Contraindications
cardiovascular diseases
fever
renal diseases
hepatic diseases
hypersensitivity
convulsion
pregnancy
Side effects
local redness
swelling
pain
fever
chills
headache
lassitude
Precautions
- shake well before use
- once freezed do not use
- not to be given for children less than 1 year
DOSAGE AND ADMINISTRATION
CHILDREN <3 YRS- 0.5 ml subcutaneous
CHILDREN.3 yrs and adult - 1.0 ml subcutaneous
ADMINISTRATION
primary immunisation
1st and 2nd dose : 2 injections at the interval of 1-2 weeks
3rd dose : after 1 year
Booster :
one dose at 6 years and 12 years
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