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Originally Posted by bharat well this time i have diffrent explanation. It is like this..
Correct ans. is B. T-lymphocyte because
T cell lymphomas occuring in the thoracic cavity in young patients usually arise in the mediastinum and have a particularly aggressive clinical course with rapid growth in the mediastinum impinging upon the trachea or mediastinum bronchi and leading to the marked respiratory deficiency, which can in turn lead to death in a relatively short period of time if not treated.
This unique lymphomas are characterised by rapid cell growth & spread in to the circulation where they produce elevated total white cell count reflacted by circulating lymphomas cell.
As T cell they have characterstics of rossete formation with SRBC.
T-cell also have CD4 helper & CD8 supressor t-cell surface antigen,the tumor cell also express IL-2 receptor
while Fc receptor occur in B-cell & macrophage, class II HLA antigen can be alsofound on macrophage,Langerhanes cell & dendritic reticular cells.
well if you want description please refer to- "Cortan, page no.654-658,661-662) |
90% of lymphomas are B-cell therefore, T-cell lymphoma 10% only which is rare. I just went according to its incidencce which is 90% for B Cell lymphoma. Yup bharat you are right. I missed age and the sex.
Yh, I missed it, only diagnostic clue was the age... since both B & T lymphomas can present with the sortness of breath due to mediastinal involvement. I missed one thing is that median age for B cell lymphomas is 30 yrs which I overlooked and for whereas T Cell Lymphoma is quite common in young males. Where as B cell in Female.