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Case Study 1: HSP - 03-07-2006, 05:13 PM

Absolutely!
The correct diagnosis is Henoch-Schonlein purpura (HSP)

Henoch-Schonlein purpura (HSP), anaphylactoid purpura:
The classic syndrome of HSP consists of a purpuric rash, arthritis, gastrointestinal symptoms, and renal involvement. Skin lesions are required for the diagnosis and often appear as small wheals or erythematous macules that progress to purpura. Angioedema of the face, hands, feet, and perineum is also common. Two thirds of the patients have arthritis in the large joints, and more than half have gastrointestinal symptoms. Colicky abdominal pain and vomiting are typical. Hemoccult results may be positive, or the stool can be grossly bloody.

The failure to recognize HSP can result in unnecessary laparotomy; however, intussusception or small-bowel obstruction rarely complicates HSP. Approximately 25-50% of the patients have renal involvement. Hematuria and proteinuria are the most common findings, but patients can have hypertension, azotemia, oliguria, or nephrotic syndrome as well. Central nervous system involvement is extremely rare.

Most patients have a benign course and require only nonsteroidal anti-inflammatory drugs (NSAIDs) for symptomatic relief. Relapses may occur. Patients with intussusception, small-bowel obstruction, or nephrotic syndrome are given prednisone 1-2 mg/kg/d and require hospitalization.

For detail informations please refer to any standard text book of Pediatrics.
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